Managed Care Guide to Crohn’s Disease : Pre-test

1.

After receiving an anti-TNF biologic for 7 yr, a patient is having diminished response. Switch to a selective IL-23 inhibitor has been prescribed, but the patient wants to know more about these medications. Which best describes results from clinical trials for patients who received a selective IL-23 inhibitor after failure on at least 1 other type of biologic therapy?

A. 10%-20% achieved clinical remission
B. 50%-60% achieved clinical remission
C. None achieved clinical remission, but they had significant improvement in quality of life
D. Only 25% achieved clinical remission, but the incidence of adverse events was the same as placebo

2.

Your organization is trying to decide whether incorporating another biologic for CD into its formulary, to provide more patient options, could provide direct economic benefit. Which of the following would provide the most accurate data for the decision?

A. Among patients not receiving medication and with frequent flares, nearly 25% are hospitalized over the course of 6 mo
B. Among patients not receiving medication and with frequent flares, about 10% visited an emergency department over the course of 6 mo
C. Compared with patients in remission, patients not in remission have about 10 more HCP visits per yr
D. Compared with patients in remission, patients not in remission are about twice as likely to undergo surgery over the course of 1 yr

3.

In patients with moderate to severe CD, starting biologic therapy >2 yr after diagnosis, compared with sooner after diagnosis, is associated with . . .

A. Higher relapse rates and similar rates of mucosal healing
B. Higher relapse rates and higher risk for surgery
C. Lower clinical remission rates and similar risk for surgery
D. Lower clinical remission rates and similar rates of mucosal healing

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Hit the Ground Running in Crohn’s Disease: A Managed Care Guide to Advanced Biologic Therapies and Early Interventions to Improve Long-term Outcomes

Bincy P. Abraham, MD, MS, AGAF, FACG, FASGE, FCCF

David Choi, PharmD, BCACP

Sheena K. Crosby, PharmD, BCGP

Pretest

Please answer the questions below.

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